Metabolomics and metabolism

NMR Spectroscopy Based Metabolomics

NMR Spectroscopy based Metabolomics provides an  intend to classify progression of toxicological actions, monitor the onset of action and organ-specific toxicity, and identify prodrugs of toxicity. The relative ease of sample preparation, its ability to quantify metabolite levels, the high level of experimental reproducibility, and the inherently nondestructive nature of NMR spectroscopy have made the platform for large-scale clinical studies. It will also explore some of the specific strengths of NMR-based metabolomics, particularly consider about isotope selection or detection, mixture of de-convolution via 2D spectroscopy, automation, and the ability to non-invasively analyze vernacular tissue specimens. It can be used for both targeted and untargeted analyses, but it is not commonly used for targeted analyses.